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Disease Modifying Anti-rheumatic Drugs (DMARDs)
Why are DMARDs used?
Disease modifying anti-rheumatic drugs (DMARDs) have mainly been used
for adults who are suffering from autoimmune conditions such as
rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis and
lupus. The immune system normally provides humans and animals with
protection from infection. An autoimmune condition is a condition
whereby the body’s own immune system starts attacking healthy tissues.
How do DMARDs work?
In contrast to most drugs, which only treat the symptoms of a
condition, DMARDs are also used to slow down the progression of
auto-immune conditions. DMARDs are thought to work partly through
suppressing immune function, although exactly how this occurs is not
known.
What are the side effects of DMARDs?
The side effects of DMARDS will depend on the particular drug taken. Side effects could include:
• abdominal cramps
• headache
• hearing loss
• hives
• emotional changes
• blurred vision
Because all DMARDS suppress immune function some people are more likely
to catch infections. It can take several weeks or months of treatment with DMARDs before the effects are noticeable. Every drug has possible
side effects and so it is important to talk with your doctor or
pharmacist about these before taking a new medication.
What drugs are classified as DMARDs?
Arava (Leflunomide)
Azasan (Azathioprine)
Azulfidine (Sulfasalazine)
Cuprimine (Penicillamine)
Depen (Penicillamine)
Folex (Methotrexate)
Imuran (Azathioprine)
Rheumatrex (Methotrexate)
Trexall (Methotrexate)
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