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Anticonvulsants
Why are anticonvulsants used?
Anticonvulsants are a diverse group of drugs that were developed for
the treatment of epileptic seizures. In more recent years,
anticonvulsants have been used to treat a range of neuropathic pain
syndromes (pain caused by dysfunction of nerve cells) including:
• Phantom limb pain
• Trigeminal neuralgia
• Diabetic neuropathy
• Multiple sclerosis
• Postherpetic neuralgia
How do anticonvulsants work?
It is still not clear exactly how anticonvulsants work. However, there
is some evidence that anticonvulsants may reduce pain by altering the
way sodium and calcium (nerve signalling molecules) travel across the
surface of nerve cells, which may disrupt signals that are sent along
the pain pathways.
What are the side effects of anticonvulsants?
It is important to remember that side effects will depend on the type
of anticonvulsant that you are taking. Some of the possible side
effects of anticonvulsants include:
• Tiredness
• Headache
• Nausea
• Changes in appetite
• Mild tremors
• Abdominal cramping
• Sleeplessness
• Mild dizziness
• Constipation
• Heartburn
• Aching joints and muscles
• Dry mouth
• Unpleasant taste in mouth
Every drug has possible side effects and so it is important to talk
with your doctor or pharmacist about possible side effects before
taking a new medication.
What drugs are classified as anticonvulsants?
Depakene (Valproic acid)
Dilantin (Phenytoin)
Epitol (Carbamazepine)
Klonopin (Clonazepam)
Lamictal (Lamotrigine)
Neurontin (Gabapentin)
Tegretol (Carbamazepine)
Topamax (Topiramate)
Trileptal (Oxcarbazepine)
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